“After RSV infection, there are great individual differences in clinical manifestations, ranging from mild upper respiratory tract infection symptoms or otitis media to severe lower respiratory tract infection. Symptoms of upper respiratory tract infection mainly include nasal congestion, runny nose, and cough. and hoarseness, with or without fever; the symptoms of lower respiratory tract infection are mainly cough, wheezing, increased breathing rate, labored breathing and feeding difficulties. Generally speaking, viruses including new coronavirus, influenza virus and RSV Sexual lower respiratory tract infection is difficult to identify based on clinical manifestations alone, and pathogenic testing is required for differential diagnosis.” Li You said.
“Therefore, early identification of community cases and referral to hospital of sick children, especially those with low peripheral oxygen saturation, and universal access to effective and affordable immunization programs will be key to future development.” Co-authors of the study Research estimates that three-quarters of RSV-infected children’s deaths occur outside the hospital setting, said Xin Wang, an associate professor at Nanjing Medical University and the University of Edinburgh in the UK.
This figure is even larger in low- and middle-income countries, especially in children under 6 months, where more than 80% of deaths occur in the community.
The impact of these data cannot be underestimated, wrote Tina Hart, a professor at Vanderbilt University School of Medicine in a commentary. This highlights the potential for passive immunization strategies to have meaningful impacts on child health in low- and middle-income countries. Accurate estimates of the impact of prevention are critical to justify the investment case for RSV prevention.
Post time: May-27-2022